Log in
Language:

MERAL Myanmar Education Research and Learning Portal

  • Top
  • Universities
  • Ranking
To
lat lon distance
To

Field does not validate



Index Link

Index Tree

Please input email address.

WEKO

One fine body…

WEKO

One fine body…

Item

{"_buckets": {"deposit": "6dc35ca8-67d4-4b33-9dfe-4f4ce56e6081"}, "_deposit": {"created_by": 235, "id": "9412", "owner": "235", "owners": [235], "owners_ext": {"displayname": "", "username": ""}, "pid": {"revision_id": 0, "type": "depid", "value": "9412"}, "status": "published"}, "_oai": {"id": "oai:meral.edu.mm:recid/00009412", "sets": []}, "author_link": [], "control_number": "9412", "item_1583103067471": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent", "subitem_1551255648112": "en"}]}, "item_1583103085720": {"attribute_name": "Description", "attribute_value_mlt": [{"interim": "Abstract\nIn this study, nanocomposite hydrogel beads were prepared by combining carboxymethyl cellulose (CMC), chitosan (CS), and ZnO nanoparticles (ZnO NPs). The obtained nanocomposite hydrogel beads were used as a potential candidate for controlled release of anticancer drug doxorubicin (DOX). The nanocomposite hydrogel beads were characterized using FT-IR, XRD, UV–vis, SEM, TG-DTA analysis. Then antimicrobial activity of the nanocomposite hydrogel beads was tested for the purpose of using nanocomposite hydrogel beads in biomedical application. In addition, gel content, swelling properties, and drug release of the samples were evaluated. The swelling and drug release profiles revealed that the amount of drug released and swelling of the hydrogels depended on the CMC/CS content, pH, and ZnO nanoparticle content. Prolonged and more controlled drug releases were observed for ZnO nanoparticle containing CMC/CS beads, which increased with the rise in ZnO nanoparticle content."}]}, "item_1583103108160": {"attribute_name": "Keywords", "attribute_value_mlt": [{"interim": "nanocomposite hydrogel beads"}, {"interim": "carboxymethyl cellulose"}, {"interim": "chitosan"}, {"interim": "ZnO  nanoparticles"}, {"interim": "drug release"}]}, "item_1583103120197": {"attribute_name": "Files", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2024-04-24"}], "displaytype": "preview", "download_preview_message": "", "file_order": 0, "filename": "1-DrAungThanHtwe.pdf", "filesize": [{"value": "1.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_0", "mimetype": "application/pdf", "size": 1100000.0, "url": {"url": "https://meral.edu.mm/record/9412/files/1-DrAungThanHtwe.pdf"}, "version_id": "c6bebb29-2141-49d7-9ff0-08b16855fa47"}]}, "item_1583103131163": {"attribute_name": "Journal articles", "attribute_value_mlt": [{"subitem_issue": "2023", "subitem_journal_title": "Journal of Asia Research Centre University of Yangon", "subitem_pages": "1-17", "subitem_volume": "Vol.9, No.1 \u0026 2, 2023"}]}, "item_1583105942107": {"attribute_name": "Authors", "attribute_value_mlt": [{"subitem_authors": [{"subitem_authors_fullname": "Aung Than Htwe"}, {"subitem_authors_fullname": "Hninn Wutt Yee Htun"}, {"subitem_authors_fullname": "Yamin Thet"}, {"subitem_authors_fullname": "May Thazin Kyaw"}, {"subitem_authors_fullname": "Ngwe Sin"}, {"subitem_authors_fullname": "Win Pa Pa Phyo"}, {"subitem_authors_fullname": "Cho Cho"}]}]}, "item_1583108359239": {"attribute_name": "Upload type", "attribute_value_mlt": [{"interim": "Publication"}]}, "item_1583108428133": {"attribute_name": "Publication type", "attribute_value_mlt": [{"interim": "Journal article"}]}, "item_1583159729339": {"attribute_name": "Publication date", "attribute_value": "2023-12-31"}, "item_title": "Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent", "item_type_id": "21", "owner": "235", "path": ["1582967633684"], "permalink_uri": "https://meral.edu.mm/records/9412", "pubdate": {"attribute_name": "Deposit date", "attribute_value": "2024-04-25"}, "publish_date": "2024-04-25", "publish_status": "0", "recid": "9412", "relation": {}, "relation_version_is_last": true, "title": ["Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent"], "weko_shared_id": -1}
  1. University of Yangon
  2. Department of Chemistry

Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent

https://meral.edu.mm/records/9412
https://meral.edu.mm/records/9412
4924af53-0269-4676-b423-c0f582c6ff68
6dc35ca8-67d4-4b33-9dfe-4f4ce56e6081
None
Preview
Name / File License Actions
1-DrAungThanHtwe.pdf 1-DrAungThanHtwe.pdf (1.1 MB)
license.icon
Publication type
Journal article
Upload type
Publication
Title
Title Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent
Language en
Publication date 2023-12-31
Authors
Aung Than Htwe
Hninn Wutt Yee Htun
Yamin Thet
May Thazin Kyaw
Ngwe Sin
Win Pa Pa Phyo
Cho Cho
Description
Abstract
In this study, nanocomposite hydrogel beads were prepared by combining carboxymethyl cellulose (CMC), chitosan (CS), and ZnO nanoparticles (ZnO NPs). The obtained nanocomposite hydrogel beads were used as a potential candidate for controlled release of anticancer drug doxorubicin (DOX). The nanocomposite hydrogel beads were characterized using FT-IR, XRD, UV–vis, SEM, TG-DTA analysis. Then antimicrobial activity of the nanocomposite hydrogel beads was tested for the purpose of using nanocomposite hydrogel beads in biomedical application. In addition, gel content, swelling properties, and drug release of the samples were evaluated. The swelling and drug release profiles revealed that the amount of drug released and swelling of the hydrogels depended on the CMC/CS content, pH, and ZnO nanoparticle content. Prolonged and more controlled drug releases were observed for ZnO nanoparticle containing CMC/CS beads, which increased with the rise in ZnO nanoparticle content.
Keywords
nanocomposite hydrogel beads, carboxymethyl cellulose, chitosan, ZnO nanoparticles, drug release
Journal articles
2023
Journal of Asia Research Centre University of Yangon
1-17
Vol.9, No.1 & 2, 2023
Back
0
0
views
downloads
See details
Views Downloads

Versions

Ver.1 2024-04-25 07:45:07.253605
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Export

OAI-PMH
  • OAI-PMH DublinCore
Other Formats
  • JSON

Confirm


Back to MERAL


Back to MERAL