{"created":"2024-04-24T08:05:16.037118+00:00","id":9412,"links":{},"metadata":{"_buckets":{"deposit":"6dc35ca8-67d4-4b33-9dfe-4f4ce56e6081"},"_deposit":{"created_by":235,"id":"9412","owner":"235","owners":[235],"owners_ext":{"displayname":"","email":"thaungbiakpar@gmail.com","username":""},"pid":{"revision_id":0,"type":"depid","value":"9412"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/00009412","sets":["1582963390870:1582967633684"]},"author_link":[],"control_number":"9412","item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent","subitem_1551255648112":"en"}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"Abstract\nIn this study, nanocomposite hydrogel beads were prepared by combining carboxymethyl cellulose (CMC), chitosan (CS), and ZnO nanoparticles (ZnO NPs). The obtained nanocomposite hydrogel beads were used as a potential candidate for controlled release of anticancer drug doxorubicin (DOX). The nanocomposite hydrogel beads were characterized using FT-IR, XRD, UV–vis, SEM, TG-DTA analysis. Then antimicrobial activity of the nanocomposite hydrogel beads was tested for the purpose of using nanocomposite hydrogel beads in biomedical application. In addition, gel content, swelling properties, and drug release of the samples were evaluated. The swelling and drug release profiles revealed that the amount of drug released and swelling of the hydrogels depended on the CMC/CS content, pH, and ZnO nanoparticle content. Prolonged and more controlled drug releases were observed for ZnO nanoparticle containing CMC/CS beads, which increased with the rise in ZnO nanoparticle content."}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value_mlt":[{"interim":"nanocomposite hydrogel beads"},{"interim":"carboxymethyl cellulose"},{"interim":"chitosan"},{"interim":"ZnO  nanoparticles"},{"interim":"drug release"}]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-04-24"}],"displaytype":"preview","filename":"1-DrAungThanHtwe.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://meral.edu.mm/record/9412/files/1-DrAungThanHtwe.pdf"},"version_id":"c6bebb29-2141-49d7-9ff0-08b16855fa47"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"2023","subitem_journal_title":"Journal of Asia Research Centre University of Yangon","subitem_pages":"1-17","subitem_volume":"Vol.9, No.1 & 2, 2023"}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Aung Than Htwe"},{"subitem_authors_fullname":"Hninn Wutt Yee Htun"},{"subitem_authors_fullname":"Yamin Thet"},{"subitem_authors_fullname":"May Thazin Kyaw"},{"subitem_authors_fullname":"Ngwe Sin"},{"subitem_authors_fullname":"Win Pa Pa Phyo"},{"subitem_authors_fullname":"Cho Cho"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2023-12-31"},"item_title":"Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent","item_type_id":"21","owner":"235","path":["1582967633684"],"publish_date":"2024-04-25","publish_status":"0","recid":"9412","relation_version_is_last":true,"title":["Doxorubicin-Loaded Carboxymethyl Cellulose/Chitosan/ZnO Nanocomposite Hydrogel Beads as an Anticancer Drug Carrier Agent"],"weko_creator_id":"235","weko_shared_id":-1},"updated":"2024-04-29T08:32:16.380915+00:00"}