{"_buckets": {"deposit": "1b005139-bd15-459d-a068-5ae4646badc5"}, "_deposit": {"id": "3142", "owners": [], "pid": {"revision_id": 0, "type": "recid", "value": "3142"}, "status": "published"}, "_oai": {"id": "oai:meral.edu.mm:recid/3142", "sets": ["1596631611229", "user-um1"]}, "communities": ["um1"], "item_1583103067471": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence", "subitem_1551255648112": ""}]}, "item_1583103085720": {"attribute_name": "Description", "attribute_value_mlt": [{"interim": "\u003cp\u003eGastric cancer is a significant health problem in Asia. Although the prevalence of Helicobacter pylori infection is similar in Bhutan,\u003cbr\u003e\nVietnam, andMyanmar, the incidence of gastric cancer is highest in Bhutan, followed by VietnamandMyanmar.We hypothesized\u003cbr\u003e\nthat H. pylori virulence factors contribute to the differences. The status of cagA, vacA, jhp0562, and 𝛽-(1,3)galT(jhp0563) was\u003cbr\u003e\nexamined in 371 H. pylori-infected patients from Bhutan, Vietnam, and Myanmar. Each virulence factor could not explain the\u003cbr\u003e\ndifference of the incidence of gastric cancer.However, the prevalence of quadruple-positive for cagA, vacA s1, vacA m1, and jhp0562-\u003cbr\u003e\npositive/𝛽-(1,3)galT-negative was significantly higher in Bhutan than in Vietnam andMyanmar and correlated with gastric cancer\u003cbr\u003e\nincidence. Moreover, gastritis-staging scores measured by histology of gastric mucosa were significantly higher in quadruplepositive\u003cbr\u003e\nstrains.We suggest that the cagA, vacA s1, vacA m1, and jhp0562-positive/𝛽-(1,3)galT-negative genotype may play a role in\u003cbr\u003e\nthe development of gastric cancer.\u003c/p\u003e"}]}, "item_1583103108160": {"attribute_name": "Keywords", "attribute_value": []}, "item_1583103120197": {"attribute_name": "Files", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2019-10-10"}], "displaytype": "preview", "download_preview_message": "", "file_order": 0, "filename": "The Prevalence of Helicobacter pylori Virulence Factors in Bhutan.pdf", "filesize": [{"value": "1262 Kb"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_0", "mimetype": "application/pdf", "size": 1262000.0, "url": {"url": "https://meral.edu.mm/record/3142/files/The Prevalence of Helicobacter pylori Virulence Factors in Bhutan.pdf"}, "version_id": "fadaa279-6008-4eff-bd10-e95aa8ca65f8"}]}, "item_1583103131163": {"attribute_name": "Journal articles", "attribute_value_mlt": [{"subitem_issue": "", "subitem_journal_title": "BioMed Research International", "subitem_pages": "1-8", "subitem_volume": ""}]}, "item_1583103147082": {"attribute_name": "Conference papers", "attribute_value_mlt": [{"subitem_acronym": "", "subitem_c_date": "", "subitem_conference_title": "", "subitem_part": "", "subitem_place": "", "subitem_session": "", "subitem_website": ""}]}, "item_1583103211336": {"attribute_name": "Books/reports/chapters", "attribute_value_mlt": [{"subitem_book_title": "", "subitem_isbn": "", "subitem_pages": "", "subitem_place": "", "subitem_publisher": ""}]}, "item_1583103233624": {"attribute_name": "Thesis/dissertations", "attribute_value_mlt": [{"subitem_awarding_university": "", "subitem_supervisor(s)": [{"subitem_supervisor": ""}]}]}, "item_1583105942107": {"attribute_name": "Authors", "attribute_value_mlt": [{"subitem_authors": [{"subitem_authors_fullname": "Tran Thi Huyen Trang"}, {"subitem_authors_fullname": "Seiji Shiota"}, {"subitem_authors_fullname": "Miyuki Matsuda"}, {"subitem_authors_fullname": "Tran Thanh Binh"}, {"subitem_authors_fullname": "Rumiko Suzuki"}, {"subitem_authors_fullname": "Ratha-korn Vilaichone"}, {"subitem_authors_fullname": "VarochaMahachai"}, {"subitem_authors_fullname": "Lotay Tshering"}, {"subitem_authors_fullname": "Ho D. Q. Dung"}, {"subitem_authors_fullname": "Tomohisa Uchida"}, {"subitem_authors_fullname": "OsamuMatsunari"}, {"subitem_authors_fullname": "TheinMyint"}, {"subitem_authors_fullname": "Vu Van Khien"}, {"subitem_authors_fullname": "Yoshio Yamaoka"}]}]}, "item_1583108359239": {"attribute_name": "Upload type", "attribute_value_mlt": [{"interim": "Publication"}]}, "item_1583108428133": {"attribute_name": "Publication type", "attribute_value_mlt": [{"interim": "Journal article"}]}, "item_1583159729339": {"attribute_name": "Publication date", "attribute_value": "2015-10-11"}, "item_1583159847033": {"attribute_name": "Identifier", "attribute_value": "10.5281/zenodo.3478855"}, "item_title": "The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence", "item_type_id": "21", "owner": "1", "path": ["1596631611229"], "permalink_uri": "http://hdl.handle.net/20.500.12678/0000003142", "pubdate": {"attribute_name": "Deposited date", "attribute_value": "2019-10-10"}, "publish_date": "2019-10-10", "publish_status": "0", "recid": "3142", "relation": {}, "relation_version_is_last": true, "title": ["The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence"], "weko_shared_id": -1}