{"created":"2020-08-30T20:01:53.920170+00:00","id":3142,"links":{},"metadata":{"_buckets":{"deposit":"1b005139-bd15-459d-a068-5ae4646badc5"},"_deposit":{"id":"3142","owners":[],"pid":{"revision_id":0,"type":"recid","value":"3142"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/3142","sets":["1582963366982:1596631611229"]},"communities":["um1"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence","subitem_1551255648112":""}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"<p>Gastric cancer is a significant health problem in Asia. Although the prevalence of Helicobacter pylori infection is similar in Bhutan,<br>\nVietnam, andMyanmar, the incidence of gastric cancer is highest in Bhutan, followed by VietnamandMyanmar.We hypothesized<br>\nthat H. pylori virulence factors contribute to the differences. The status of cagA, vacA, jhp0562, and 𝛽-(1,3)galT(jhp0563) was<br>\nexamined in 371 H. pylori-infected patients from Bhutan, Vietnam, and Myanmar. Each virulence factor could not explain the<br>\ndifference of the incidence of gastric cancer.However, the prevalence of quadruple-positive for cagA, vacA s1, vacA m1, and jhp0562-<br>\npositive/𝛽-(1,3)galT-negative was significantly higher in Bhutan than in Vietnam andMyanmar and correlated with gastric cancer<br>\nincidence. Moreover, gastritis-staging scores measured by histology of gastric mucosa were significantly higher in quadruplepositive<br>\nstrains.We suggest that the cagA, vacA s1, vacA m1, and jhp0562-positive/𝛽-(1,3)galT-negative genotype may play a role in<br>\nthe development of gastric cancer.</p>"}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value":[]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-10-10"}],"displaytype":"preview","filename":"The Prevalence of Helicobacter pylori Virulence Factors in Bhutan.pdf","filesize":[{"value":"1262 Kb"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://meral.edu.mm/record/3142/files/The Prevalence of Helicobacter pylori Virulence Factors in Bhutan.pdf"},"version_id":"fadaa279-6008-4eff-bd10-e95aa8ca65f8"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"","subitem_journal_title":"BioMed Research International","subitem_pages":"1-8","subitem_volume":""}]},"item_1583103147082":{"attribute_name":"Conference papers","attribute_value_mlt":[{"subitem_acronym":"","subitem_c_date":"","subitem_conference_title":"","subitem_part":"","subitem_place":"","subitem_session":"","subitem_website":""}]},"item_1583103211336":{"attribute_name":"Books/reports/chapters","attribute_value_mlt":[{"subitem_book_title":"","subitem_isbn":"","subitem_pages":"","subitem_place":"","subitem_publisher":""}]},"item_1583103233624":{"attribute_name":"Thesis/dissertations","attribute_value_mlt":[{"subitem_awarding_university":"","subitem_supervisor(s)":[{"subitem_supervisor":""}]}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Tran Thi Huyen Trang"},{"subitem_authors_fullname":"Seiji Shiota"},{"subitem_authors_fullname":"Miyuki Matsuda"},{"subitem_authors_fullname":"Tran Thanh Binh"},{"subitem_authors_fullname":"Rumiko Suzuki"},{"subitem_authors_fullname":"Ratha-korn Vilaichone"},{"subitem_authors_fullname":"VarochaMahachai"},{"subitem_authors_fullname":"Lotay Tshering"},{"subitem_authors_fullname":"Ho D. Q. Dung"},{"subitem_authors_fullname":"Tomohisa Uchida"},{"subitem_authors_fullname":"OsamuMatsunari"},{"subitem_authors_fullname":"TheinMyint"},{"subitem_authors_fullname":"Vu Van Khien"},{"subitem_authors_fullname":"Yoshio Yamaoka"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2015-10-11"},"item_1583159847033":{"attribute_name":"Identifier","attribute_value":"10.5281/zenodo.3478855"},"item_title":"The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence","item_type_id":"21","owner":"1","path":["1596631611229"],"publish_date":"2019-10-10","publish_status":"0","recid":"3142","relation_version_is_last":true,"title":["The Prevalence of Helicobacter pylori Virulence Factors in Bhutan, Vietnam, and Myanmar Is Related to Gastric Cancer Incidence"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-03-24T23:17:19.858412+00:00"}