{"_buckets": {"deposit": "f95c92b6-93b0-4ef5-a6eb-52144efb5760"}, "_deposit": {"id": "3132", "owners": [], "pid": {"revision_id": 0, "type": "recid", "value": "3132"}, "status": "published"}, "_oai": {"id": "oai:meral.edu.mm:recid/3132", "sets": ["user-um1"]}, "communities": ["um1"], "item_1583103067471": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages", "subitem_1551255648112": ""}]}, "item_1583103085720": {"attribute_name": "Description", "attribute_value_mlt": [{"interim": "\u003cp\u003eThe ACAT gene was first cloned in 1993 (Chang et al., J. Biol. Chem. 1993;268:20747-20755; designated as ACAT-1). Using affinity purified antibodies raised against N-terminal portion of human ACAT-1 protein, we performed immunohistochemical localization studies, and showed that the ACAT-1 protein was highly expressed in the atherosclerotic lesions of human aorta. We also performed cell-specific localization studies using double immunostaining, and showed that ACAT-1 was predominantly expressed in macrophages, but not in smooth muscle cells. We then used cell culture system in vitro to monitor the ACAT-1 expression in differentiating monocytes-macrophages\u003c/p\u003e"}]}, "item_1583103108160": {"attribute_name": "Keywords", "attribute_value": []}, "item_1583103120197": {"attribute_name": "Files", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2019-08-22"}], "displaytype": "preview", "download_preview_message": "", "file_order": 0, "filename": "Expression of ACAT.pdf", "filesize": [{"value": "85 Kb"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_0", "mimetype": "application/pdf", "size": 85000.0, "url": {"url": "https://meral.edu.mm/record/3132/files/Expression of ACAT.pdf"}, "version_id": "c93d76cf-50f8-48aa-a905-1d336e55704c"}]}, "item_1583103131163": {"attribute_name": "Journal articles", "attribute_value_mlt": [{"subitem_issue": "", "subitem_journal_title": "Lipoprotein Metabolism and Atherogenesis", "subitem_pages": "142-153", "subitem_volume": ""}]}, "item_1583103147082": {"attribute_name": "Conference papers", "attribute_value_mlt": [{"subitem_acronym": "", "subitem_c_date": "", "subitem_conference_title": "", "subitem_part": "", "subitem_place": "", "subitem_session": "", "subitem_website": ""}]}, "item_1583103211336": {"attribute_name": "Books/reports/chapters", "attribute_value_mlt": [{"subitem_book_title": "", "subitem_isbn": "", "subitem_pages": "", "subitem_place": "", "subitem_publisher": ""}]}, "item_1583103233624": {"attribute_name": "Thesis/dissertations", "attribute_value_mlt": [{"subitem_awarding_university": "", "subitem_supervisor(s)": [{"subitem_supervisor": ""}]}]}, "item_1583105942107": {"attribute_name": "Authors", "attribute_value_mlt": [{"subitem_authors": [{"subitem_authors_fullname": "Akira Miyazaki"}, {"subitem_authors_fullname": "Naomi Sakashita"}, {"subitem_authors_fullname": "Kyu Kyu Maung"}, {"subitem_authors_fullname": "Kiyoshi Takahashi"}, {"subitem_authors_fullname": "Seikoh Horiuchi"}, {"subitem_authors_fullname": "C. C. Y. Chang"}, {"subitem_authors_fullname": "T. Y. Chang"}]}]}, "item_1583108359239": {"attribute_name": "Upload type", "attribute_value_mlt": [{"interim": "Publication"}]}, "item_1583108428133": {"attribute_name": "Publication type", "attribute_value_mlt": [{"interim": "Journal article"}]}, "item_1583159729339": {"attribute_name": "Publication date", "attribute_value": "2000-08-05"}, "item_1583159847033": {"attribute_name": "Identifier", "attribute_value": "10.5281/zenodo.3374398"}, "item_title": "Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages", "item_type_id": "21", "owner": "1", "path": ["1597649530495"], "permalink_uri": "http://hdl.handle.net/20.500.12678/0000003132", "pubdate": {"attribute_name": "Deposited date", "attribute_value": "2019-08-22"}, "publish_date": "2019-08-22", "publish_status": "0", "recid": "3132", "relation": {}, "relation_version_is_last": true, "title": ["Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages"], "weko_shared_id": -1}