{"created":"2020-08-30T20:01:00.644840+00:00","id":3132,"links":{},"metadata":{"_buckets":{"deposit":"f95c92b6-93b0-4ef5-a6eb-52144efb5760"},"_deposit":{"id":"3132","owners":[],"pid":{"revision_id":0,"type":"recid","value":"3132"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/3132","sets":["1582963366982:1597649530495"]},"communities":["um1"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages","subitem_1551255648112":""}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"<p>The ACAT gene was first cloned in 1993 (Chang et al., J. Biol. Chem. 1993;268:20747-20755; designated as ACAT-1). Using affinity purified antibodies raised against N-terminal portion of human ACAT-1 protein, we performed immunohistochemical localization studies, and showed that the ACAT-1 protein was highly expressed in the atherosclerotic lesions of human aorta. We also performed cell-specific localization studies using double immunostaining, and showed that ACAT-1 was predominantly expressed in macrophages, but not in smooth muscle cells. We then used cell culture system in vitro to monitor the ACAT-1 expression in differentiating monocytes-macrophages</p>"}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value":[]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-08-22"}],"displaytype":"preview","filename":"Expression of ACAT.pdf","filesize":[{"value":"85 Kb"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://meral.edu.mm/record/3132/files/Expression of ACAT.pdf"},"version_id":"c93d76cf-50f8-48aa-a905-1d336e55704c"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"","subitem_journal_title":"Lipoprotein Metabolism and Atherogenesis","subitem_pages":"142-153","subitem_volume":""}]},"item_1583103147082":{"attribute_name":"Conference papers","attribute_value_mlt":[{"subitem_acronym":"","subitem_c_date":"","subitem_conference_title":"","subitem_part":"","subitem_place":"","subitem_session":"","subitem_website":""}]},"item_1583103211336":{"attribute_name":"Books/reports/chapters","attribute_value_mlt":[{"subitem_book_title":"","subitem_isbn":"","subitem_pages":"","subitem_place":"","subitem_publisher":""}]},"item_1583103233624":{"attribute_name":"Thesis/dissertations","attribute_value_mlt":[{"subitem_awarding_university":"","subitem_supervisor(s)":[{"subitem_supervisor":""}]}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Akira Miyazaki"},{"subitem_authors_fullname":"Naomi Sakashita"},{"subitem_authors_fullname":"Kyu Kyu Maung"},{"subitem_authors_fullname":"Kiyoshi Takahashi"},{"subitem_authors_fullname":"Seikoh Horiuchi"},{"subitem_authors_fullname":"C. C. Y. Chang"},{"subitem_authors_fullname":"T. Y. Chang"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2000-08-05"},"item_1583159847033":{"attribute_name":"Identifier","attribute_value":"10.5281/zenodo.3374398"},"item_title":"Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages","item_type_id":"21","owner":"1","path":["1597649530495"],"publish_date":"2019-08-22","publish_status":"0","recid":"3132","relation_version_is_last":true,"title":["Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2021-12-13T05:48:31.785117+00:00"}