{"_buckets": {"deposit": "75362471-20ba-45e7-91cf-a544000931d7"}, "_deposit": {"created_by": 12, "id": "9366", "owner": "12", "owners": [12], "owners_ext": {"displayname": "", "username": ""}, "pid": {"revision_id": 0, "type": "depid", "value": "9366"}, "status": "published"}, "_oai": {"id": "oai:meral.edu.mm:recid/00009366"}, "author_link": [], "item_1583103067471": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "Evaluation of Antioxidant Capacity, Antimicrobial, Anticancer Activities, and Phytochemical Investigation of Male Papaya Leaves (Carica papaya L.)", "subitem_1551255648112": "en"}]}, "item_1583103085720": {"attribute_name": "Description", "attribute_value_mlt": [{"interim": "Cancer is one of the most dangerous diseases in humans and there has been a scientific discovery of anticancer agents from natural products. Several bioassays such as antimicrobial, antioxidant, and anti-cancer activities were determined. The main aim of the present research was to evaluate the biological properties of male Papaya leaves. The preliminary phytochemical tests indicated that various types of compounds such as alkaloids, glycosides, phenolic compounds, flavonoids, tannins, steroids, terpenoids, saponins, starch, carbohydrates, and α-amino acids were found to be present but cyanogenic glycosides and reducing sugars were not detected in Carica papaya L. leaves. The total phenols content of ethanol extract (7.92 μg GAE/mg) was higher than that of watery extract (4.654 μg GAE/mg) by the FCR Method. The total flavonoid content of ethanol extract (12.35 μg GAE/mg) was higher than that of watery extract (7.6 μg GAE/mg) by Aluminium Chloride Colorimetric Assay. The antioxidant capacity of the ethanol and watery extracts from leaves was studied by using the DPPH free radical scavenging assay. The antioxidant activity of ethanol extract (IC50 18.52 μg/mL) was found to be higher than that of watery extract (IC50 19.93 μg/mL). The antimicrobial activity of various crude extracts was screened by the Agar Disc Diffusion method. Watery extract (15-40 mm) showed antimicrobial activity against Agrobacterium tumefaciens, Bacillus subtilis, Candida albicans, Escherichia coli, and Pseudomonas fluorescence. In the case of Pseudomonas fluorescence, the antimicrobial activity of PE extract (59.5 mm) was inhibited more than standard medicine chloramphenicol (42.2 mm). In vitro antiproliferative activities of ethanol and watery extracts of the C. papaya L. leaves were investigated against human lung cancer and human cervix cancer by the CCK-8 assay. The IC50 values of ethanol and watery extracts for human lung cancer and human cervix cancer were observed to be greater than 200 μg/mL. Therefore, male Papaya leaves (C. papaya L.) may be used for preventing diseases caused by bacteria and also as an antioxidant agent."}]}, "item_1583103108160": {"attribute_name": "Keywords", "attribute_value_mlt": [{"interim": "Carica papaya L."}, {"interim": "antioxidant"}, {"interim": "anticancer"}, {"interim": "antimicrobial"}]}, "item_1583103120197": {"attribute_name": "Files", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2024-03-15"}], "displaytype": "preview", "download_preview_message": "", "file_order": 0, "filename": "San San Aye (357 to 366).pdf", "filesize": [{"value": "365 KB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_3", "mimetype": "application/pdf", "size": 365000.0, "url": {"url": "https://meral.edu.mm/record/9366/files/San San Aye (357 to 366).pdf"}, "version_id": "6740c9b1-0f5a-4add-aec6-0f897b373884"}]}, "item_1583103131163": {"attribute_name": "Journal articles", "attribute_value_mlt": [{"subitem_issue": "2022", "subitem_journal_title": "University of Yangon Research Journal", "subitem_pages": "357-366", "subitem_volume": "11, No. 1"}]}, "item_1583105942107": {"attribute_name": "Authors", "attribute_value_mlt": [{"subitem_authors": [{"subitem_authors_fullname": "San San Aye1"}, {"subitem_authors_fullname": "Myat Kaythi Phyo2"}, {"subitem_authors_fullname": "Ei Ei San3"}, {"subitem_authors_fullname": "Ni Ni Than4"}]}]}, "item_1583108359239": {"attribute_name": "Upload type", "attribute_value_mlt": [{"interim": "Publication"}]}, "item_1583108428133": {"attribute_name": "Publication type", "attribute_value_mlt": [{"interim": "Journal article"}]}, "item_1583159729339": {"attribute_name": "Publication date", "attribute_value": "2022-12-31"}, "item_title": "Evaluation of Antioxidant Capacity, Antimicrobial, Anticancer Activities, and Phytochemical Investigation of Male Papaya Leaves (Carica papaya L.)", "item_type_id": "21", "owner": "12", "path": ["1582967633684"], "permalink_uri": "https://meral.edu.mm/records/9366", "pubdate": {"attribute_name": "Deposit date", "attribute_value": "2024-03-15"}, "publish_date": "2024-03-15", "publish_status": "0", "recid": "9366", "relation": {}, "relation_version_is_last": true, "title": ["Evaluation of Antioxidant Capacity, Antimicrobial, Anticancer Activities, and Phytochemical Investigation of Male Papaya Leaves (Carica papaya L.)"], "weko_shared_id": -1}