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All cases were neonates admitted for treatment of jaundice between March 2013 and February 2014 and who required an exchange transfusion. Each control was the next noncase neonate admitted for treatment of jaundice and treated with phototherapy. Infant characteristics, pathways of admission and clinically relevant factors for exchange transfusion were collected.\nResults: One hundred thirty-four cases and 134 controls were included in the study. Among cases, home was the most common place of birth while public hospital was the most frequent source of referral. Among controls, private/public hospitals were the commonest places of birth and referral. At multivariable analysis, homebirth was associated with increased likelihood of receiving exchange transfusion at admission (OR 3.30, 95% C.I. 1.31–8.56).\nConclusion: Homebirth was an independent risk factor for exchange transfusion at admission for jaundice in a low-resource setting. Appropriate health education of pregnant women and traditional/home birth attendants may contribute to reduce the need for exchange transfusion in low-resource settings."}, {"interim": "The study was conducted during a development program in Myanmar of Amici della Neonatologia Trentina, ANT ONLUS (Trento, Italy), with cofinancing from the Department of European Integration and Humanitarian Aid of the Region Trentino Alto Adige (Italy), in partnership with Thrive Networks (CA, USA) and Eric Hemel and Barbara Morgen, private donors. 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  1. University of Medicine 1
  2. Department of Neonatology
  1. University of Medicine 2

Birthplace is a risk factor for exchange transfusion in outborn infants admitted for jaundice in Myanmar: a case-control study

http://hdl.handle.net/20.500.12678/0000008012
http://hdl.handle.net/20.500.12678/0000008012
d18dbea1-2cd2-46af-9aea-4ab09cbac83c
333bf3aa-3694-47c5-8b9b-7f16886727f8
None
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Birthplace Birthplace is a risk factor for exchange transfusion in outborn infants admitted for jaundice in Myanmar.pdf (854 KB)
© 2018 Informa UK Limited, trading as Taylor & Francis Group
Publication type
Journal article
Upload type
Publication
Title
Title Birthplace is a risk factor for exchange transfusion in outborn infants admitted for jaundice in Myanmar: a case-control study
Language en
Publication date 2018-11-11
Authors
Cavallin, Francesco
Trevisanuto, Daniele
Aye Thein
Booth, Amanda
Arnolda, Gaston
Kumara, Danica
Phyu U
Sandar Myint
Moccia, Luciano
Description
Aim: To evaluate the role of pathway to admission for jaundice among the risk factors for exchange transfusion in outborn infants in a low resource setting.
Methods: This retrospective case-control study (1:1 ratio) was carried out at the Yankin Children’s Hospital in Yangon (Myanmar). All cases were neonates admitted for treatment of jaundice between March 2013 and February 2014 and who required an exchange transfusion. Each control was the next noncase neonate admitted for treatment of jaundice and treated with phototherapy. Infant characteristics, pathways of admission and clinically relevant factors for exchange transfusion were collected.
Results: One hundred thirty-four cases and 134 controls were included in the study. Among cases, home was the most common place of birth while public hospital was the most frequent source of referral. Among controls, private/public hospitals were the commonest places of birth and referral. At multivariable analysis, homebirth was associated with increased likelihood of receiving exchange transfusion at admission (OR 3.30, 95% C.I. 1.31–8.56).
Conclusion: Homebirth was an independent risk factor for exchange transfusion at admission for jaundice in a low-resource setting. Appropriate health education of pregnant women and traditional/home birth attendants may contribute to reduce the need for exchange transfusion in low-resource settings.
The study was conducted during a development program in Myanmar of Amici della Neonatologia Trentina, ANT ONLUS (Trento, Italy), with cofinancing from the Department of European Integration and Humanitarian Aid of the Region Trentino Alto Adige (Italy), in partnership with Thrive Networks (CA, USA) and Eric Hemel and Barbara Morgen, private donors. The funders had no role in the design, conduct, or decision to submit the study for publication
Keywords
exchange transfusion, jaundice, low-resource setting, phototherapy
Identifier 10.1080/14767058.2018.1521796
Journal articles
9
The Journal of Maternal-Fetal & Neonatal Medicine
1009-1009
33
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