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  1. University of Medicine 2
  2. Department of Medicine

The clinical characteristics of adults with rheumatic heart disease in Yangon, Myanmar: Anobservation a lstudy

http://hdl.handle.net/20.500.12678/0000007879
http://hdl.handle.net/20.500.12678/0000007879
874cd80b-3eaa-40ea-ad5d-580383275e7f
6f1c4a8b-e673-4f01-914d-563ee670d4bf
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The_clinical_characteristics_of_adults_with_rheuma.pdf The_clinical_characteristics_of_adults_with_rheuma.pdf (1.5 MB)
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Publication type
Journal article
Upload type
Publication
Title
Title The clinical characteristics of adults with rheumatic heart disease in Yangon, Myanmar: Anobservation a lstudy
Language en
Publication date 2018-02-21
Authors
Nan Phyu Sin Toe Myint
Ne Myo Aung
Myint Soe Win
Thu Ya Htut
Ralph, Anna P.
Cooper, David A.
Myo Lwin Nyein
Mar Mar Kyi
Hanson, Josh
Description
BackgroundRheumaticheartdisease(RHD)is a majorcauseof prematuredeathin lowandmiddle-incomecountries.Thegreatestbarrierto RHDcontrolis neglectof thediseasein nationalhealthpoliciesanda lackof prevalencedatathatmightinformcontrolefforts.Myanmarismakingremarkableprogressagainstmanyinfectiousdiseases,buttherearealmostnodatato definetheclinicalburdenof RHDin thecountry.Thisprospective auditwasperformedinanadultmedicalwardof a tertiary-referralhospitalin Yangon,to gainaninsightintotheprevalenceof RHDin Myanmar.PrincipalfindingsAllpatientsadmittedto thewardbetweenMay1, 2016andApril30,2017wereeligibleforenrolment.RHDwasconfirmedin 96patientswhowereadmittedon134occasions,repre-senting1.1%of the12,172adultmedicaladmissionsduringthestudyperiod.Thiscom-paredwith410(3.4%)admissionswithHIVand14(0.1%)withmalaria.PatientswithRHDhada medianageof 44years(interquartilerange:35–59);70(73%)werefemale.Onlyonepatienthadeverhadsurgerydespite79(82%)meetingcriteriaforintervention;54(56%)patientswerenotreceivinganyregularclinicianreview.Priorto hospitalisationonly18(19%)patientswerereceivingregularpenicillin.Only8 (19%)of the42women<50yearswereusingcontraception.Of49patientswhohadbeenhospitalisedpreviously,22(45%)werereceivingnoregulartherapy.Duringthestudythree(3.1%)patientsdied,and28(29%)werelostto follow-up.Ofthe65(68%)aliveandretainedin care,21(32%)werestillexperiencingmoderate-severeRHD-relatedsymptomsat thestudy’send.ConclusionsThereis a significantandunmetclinicalburdenof RHDin Myanmar.A nationalRHDprogram-mewouldimprovepatientcare,reducingmorbidityandmortalityfromthispreventabledisease.
Keywords
Heart Disease, Rheumatology
Identifier https://doi.org/10.1371/journal.pone.0192880
Journal articles
13
PLoSONE
1-14
2
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