{"_buckets": {"deposit": "0bf4727c-9820-46ad-8530-ac625c1f6f3a"}, "_deposit": {"created_by": 130, "id": "7289", "owner": "130", "owners": [130], "owners_ext": {"displayname": "", "username": ""}, "pid": {"revision_id": 0, "type": "depid", "value": "7289"}, "status": "published"}, "_oai": {"id": "oai:meral.edu.mm:recid/00007289", "sets": ["user-udmy"]}, "communities": ["udmy"], "item_1583103067471": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "Efficacy of the Autofluorescence-based Imaging System (VELscopeTM) in Detection of Oral Potentially Malignant Disorders", "subitem_1551255648112": "en"}]}, "item_1583103085720": {"attribute_name": "Description", "attribute_value_mlt": [{"interim": "The occurrence of oral potentially malignant disorders (OPMDs) has ascended in developing countries where the usage of betel quid chewing and tobacco is accustomed. Despite the developing advanced treatment procedures, malignant transformation rate of some of the OPMDs is considerably high (4 to 18%) according to the recent studies. Hence, adjunctive diagnostic aids for early detection of oral cancer have been developed to help the practitioners in identifying high-risk OPMDs. VELscopeTM is a one of the diagnostic adjuncts, which is non-invasive, handheld device designed to visualize early mucosal changes using the principles of tissue autofluorescence. The objective of the study was to determine the efficacy of VELscopeTM in detection of OPMDs. Fifty-seven patients with OPMDs seeking treatment at University of Dental Medicine, Yangon were included in this study. After obtaining the informed consent, detailed clinical history was taken and thorough conventional oral examination (COE) was performed. The area of OPMDs was visualized by VELscopeTM and the fluorescent visualization loss (FVL) was recorded. An incisional biopsy was performed at the FVL are for histopathological examination. VELscopeTM results and histopathological results were compared and sensitivity and specificity were calculated. Mean age of the patients in this study were 37.54±12.78 and male to female ratio was 2:1. According to this study, sensitivity of VELscopeTM was 94.4% and specificity was 23.8%. Positive predictive value was 68.0% and negative predictive value was 71.4%.Results of the study revealed that VELscopeTM has an optimistic potential as a clinical auxiliary method in detecting OPMDs before performing a biopsy. This device may be an effective adjunct in community oral cancer screening when used with proper clinical judgment. This study suggests for future studies with two scenarios: first with larger sample size, for instance, population-based oral cancer screening and the second with hospitalbased clinical studies with determination of marginal clearance using VELscopeTM."}]}, "item_1583103108160": {"attribute_name": "Keywords", "attribute_value_mlt": [{"interim": "oral potentially malignant disorders"}, {"interim": "VELscope,"}, {"interim": "autofluorescence"}, {"interim": "Optical Imaging"}]}, "item_1583103120197": {"attribute_name": "Files", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2021-01-07"}], "displaytype": "preview", "download_preview_message": "", "file_order": 0, "filename": "07-Efficacy_of_the_Authofluorescence-based_Imanging_System_(VELscopeTM)_in_Detection_of_Oral_Potentially_Malignant_Disorders_(Dr_ZMT,_Dr_KMDK,_Dr_MTDH,_Dr_TT,_Dr_NDA,_Dr_AAT)1.pdf", "filesize": [{"value": "497 KB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_0", "mimetype": "application/pdf", "size": 497000.0, "url": {"url": "https://meral.edu.mm/record/7289/files/07-Efficacy_of_the_Authofluorescence-based_Imanging_System_(VELscopeTM)_in_Detection_of_Oral_Potentially_Malignant_Disorders_(Dr_ZMT,_Dr_KMDK,_Dr_MTDH,_Dr_TT,_Dr_NDA,_Dr_AAT)1.pdf"}, "version_id": "b71aae29-283c-43f8-8891-572c990fc8d0"}]}, "item_1583103131163": {"attribute_name": "Journal articles", "attribute_value_mlt": [{"subitem_issue": "No.1", "subitem_journal_title": "Journal of Dental Science-UDMY", "subitem_pages": "49-56", "subitem_volume": "Vol.1"}]}, "item_1583105942107": {"attribute_name": "Authors", "attribute_value_mlt": [{"subitem_authors": [{"subitem_authors_fullname": "Zaw Moe Thein"}, {"subitem_authors_fullname": "Kumudra Kyaw"}, {"subitem_authors_fullname": "Moe Thida Htwe"}, {"subitem_authors_fullname": "Thein Tun"}, {"subitem_authors_fullname": "Nandar Aung"}, {"subitem_authors_fullname": "Aye Aye Thet"}, {"subitem_authors_fullname": "Shwe Toe"}]}]}, "item_1583108359239": {"attribute_name": "Upload type", "attribute_value_mlt": [{"interim": "Publication"}]}, "item_1583108428133": {"attribute_name": "Publication type", "attribute_value_mlt": [{"interim": "Journal article"}]}, "item_1583159729339": {"attribute_name": "Publication date", "attribute_value": "2021-01-07"}, "item_1583159847033": {"attribute_name": "Identifier", "attribute_value": "http://udmyangon-edu.com"}, "item_title": "Efficacy of the Autofluorescence-based Imaging System (VELscopeTM) in Detection of Oral Potentially Malignant Disorders", "item_type_id": "21", "owner": "130", "path": ["1608059108263"], "permalink_uri": "http://hdl.handle.net/20.500.12678/0000007289", "pubdate": {"attribute_name": "Deposited date", "attribute_value": "2021-01-07"}, "publish_date": "2021-01-07", "publish_status": "0", "recid": "7289", "relation": {}, "relation_version_is_last": true, "title": ["Efficacy of the Autofluorescence-based Imaging System (VELscopeTM) in Detection of Oral Potentially Malignant Disorders"], "weko_shared_id": -1}