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  1. University of Medicine 1
  2. Department of Microbiology

Genome-Wide Analyses of Individual Strongyloides stercoralis (Nematoda: Rhabditoidea) Provide Insights into Population Structure and Reproductive Life Cycles

http://hdl.handle.net/20.500.12678/0000003150
http://hdl.handle.net/20.500.12678/0000003150
178694c7-9e21-4890-9ed5-988eb72f8727
e102d99e-52f0-45eb-8c31-221eb18a859d
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5.Genome-Wide 5.Genome-Wide Analyses of Individual.pdf (2466 Kb)
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Publication type
Journal article
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Publication
Title
Title Genome-Wide Analyses of Individual Strongyloides stercoralis (Nematoda: Rhabditoidea) Provide Insights into Population Structure and Reproductive Life Cycles
Publication date 2016-10-10
Authors
Taisei Kikuchi
Akina Hino
Teruhisa Tanaka
Myo Pa Pa Thet Hnin Htwe Aung
Tanzila Afrin
Eiji Nagayasu
Ryusei Tanaka
Miwa Higashiarakawa
Kyu Kyu Win
Tetsuo Hirata
Wah Win Htike
Jiro Fujita
Haruhiko Maruyama
Description
<p>The helminth Strongyloides stercoralis, which is transmitted through soil, infects 30&plusmn;100 million&nbsp;people worldwide. S. stercoralis reproduces sexually outside the host as well as asexually&nbsp;within the host, which causes a life-long infection. To understand the population structure and&nbsp;transmission patterns of this parasite, we re-sequenced the genomes of 33 individual S. stercoralis<br>
nematodes collected in Myanmar (prevalent region) and Japan (non-prevalent region).&nbsp;We utilised a method combining whole genome amplification and next-generation sequencing&nbsp;techniques to detect 298,202 variant positions (0.6% of the genome) compared with the reference&nbsp;genome.</p>
Keywords
strongyloides stercoralis
Identifier 10.5281/zenodo.3531195
Journal articles
Neglected Tropical Diseases
1-15
Conference papers
Books/reports/chapters
Thesis/dissertations
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