{"_buckets": {"deposit": "b62bae2f-7dd7-4547-9104-9b0663eca910"}, "_deposit": {"id": "3127", "owners": [], "pid": {"revision_id": 0, "type": "recid", "value": "3127"}, "status": "published"}, "_oai": {"id": "oai:meral.edu.mm:recid/3127", "sets": ["user-um1"]}, "communities": ["um1"], "item_1583103067471": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "Single Nucleotide Polymorphism at +276 G\u003eT of the Adiponectin Gene and Plasma Adiponectin Level in Myanmar Type 2 Diabetic Patients", "subitem_1551255648112": ""}]}, "item_1583103085720": {"attribute_name": "Description", "attribute_value_mlt": [{"interim": "\u003cp\u003eAbstract\u003cbr\u003e\nObjective. The aim of the study was to investigate the association between single nucleotide polymorphisms (SNP) at\u003cbr\u003e\nrs 1501299 (SNP+276 G\u0026gt;T) of the adiponectin gene and plasma adiponectin levels in type 2 diabetes mellitus (T2DM)\u003cbr\u003e\npatients in Myanmar.\u003cbr\u003e\nMethodology. One hundred T2DM patients and 104 non-diabetic subjects were included in this cross-sectional analytical\u003cbr\u003e\nstudy. Genotype frequencies were determined by polymerase chain reaction - restriction fragment length polymorphism\u003cbr\u003e\n(PCR-RFLP) method. Plasma adiponectin level was measured by enzyme-linked immunosorbent assay (ELISA).\u003cbr\u003e\nResult. Genotype frequencies (GG, GT, TT) of SNP+276 in diabetic patients were 39%, 48% and 13%, respectively. The\u003cbr\u003e\nGT and TT genotypes were more frequent in T2DM patients (OR 1.98, 95% CI, 1.10-3.55; p=0.02 and OR 4.07, 95%\u003cbr\u003e\nCI, 1.34-12.3; p=0.01), respectively. The T allele of SNP+276 was significantly associated with T2DM (OR 1.96, 95% CI,\u003cbr\u003e\n1.27-3.01; p=0.002). Mean plasma adiponectin level was significantly lower than in T2DM patients (27.41\u0026plusmn;16.7 \u0026mu;g/mL)\u003cbr\u003e\ncompared to non-diabetic subjects (37.19\u0026plusmn;26.77 \u0026mu;g/mL) (p=0.002).\u003cbr\u003e\nConclusion. SNP+276 at rs 1501299 of the adiponectin gene was associated with type 2 diabetes and low plasma\u003cbr\u003e\nadiponectin levels in this Myanmar population.\u003c/p\u003e"}]}, "item_1583103108160": {"attribute_name": "Keywords", "attribute_value_mlt": [{"interim": "adiponectin gene"}]}, "item_1583103120197": {"attribute_name": "Files", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2019-08-21"}], "displaytype": "preview", "download_preview_message": "", "file_order": 0, "filename": "Single Nucleotide Polymorphism at  276 G T of the Adiponectin Gene.pdf", "filesize": [{"value": "1048 Kb"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_0", "mimetype": "application/pdf", "size": 1048000.0, "url": {"url": "https://meral.edu.mm/record/3127/files/Single Nucleotide Polymorphism at  276 G T of the Adiponectin Gene.pdf"}, "version_id": "a52b1333-798d-4117-ad4b-719a4931547a"}]}, "item_1583103131163": {"attribute_name": "Journal articles", "attribute_value_mlt": [{"subitem_issue": "2", "subitem_journal_title": "Journal of the ASEAN Federation of Endocrine Societies", "subitem_pages": "160-164", "subitem_volume": "33"}]}, "item_1583103147082": {"attribute_name": "Conference papers", "attribute_value_mlt": [{"subitem_acronym": "", "subitem_c_date": "", "subitem_conference_title": "", "subitem_part": "", "subitem_place": "", "subitem_session": "", "subitem_website": ""}]}, "item_1583103211336": {"attribute_name": "Books/reports/chapters", "attribute_value_mlt": [{"subitem_book_title": "", "subitem_isbn": "", "subitem_pages": "", "subitem_place": "", "subitem_publisher": ""}]}, "item_1583103233624": {"attribute_name": "Thesis/dissertations", "attribute_value_mlt": [{"subitem_awarding_university": "", "subitem_supervisor(s)": [{"subitem_supervisor": ""}]}]}, "item_1583105942107": {"attribute_name": "Authors", "attribute_value_mlt": [{"subitem_authors": [{"subitem_authors_fullname": "Khin Thin Yu"}, {"subitem_authors_fullname": "Kyu Kyu Maung"}, {"subitem_authors_fullname": "Aye Thida"}, {"subitem_authors_fullname": "Thein Myint"}]}]}, "item_1583108359239": {"attribute_name": "Upload type", "attribute_value_mlt": [{"interim": "Publication"}]}, "item_1583108428133": {"attribute_name": "Publication type", "attribute_value_mlt": [{"interim": "Journal article"}]}, "item_1583159729339": {"attribute_name": "Publication date", "attribute_value": "2018-11-28"}, "item_1583159847033": {"attribute_name": "Identifier", "attribute_value": "10.5281/zenodo.3373308"}, "item_title": "Single Nucleotide Polymorphism at +276 G\u003eT of the Adiponectin Gene and Plasma Adiponectin Level in Myanmar Type 2 Diabetic Patients", "item_type_id": "21", "owner": "1", "path": ["1597649530495"], "permalink_uri": "http://hdl.handle.net/20.500.12678/0000003127", "pubdate": {"attribute_name": "Deposited date", "attribute_value": "2019-08-21"}, "publish_date": "2019-08-21", "publish_status": "0", "recid": "3127", "relation": {}, "relation_version_is_last": true, "title": ["Single Nucleotide Polymorphism at +276 G\u003eT of the Adiponectin Gene and Plasma Adiponectin Level in Myanmar Type 2 Diabetic Patients"], "weko_shared_id": -1}