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Niruriflavone, a new Antioxidant Flavone Sulfonic Acid from Phyllanthus niruri
http://hdl.handle.net/20.500.126780000002622
b42139ff-a850-4a0e-a7e2-4fdba0748af5
0966e4ea-7820-4ef7-8e29-4e586d4dcda3
Name / File | License | Actions | |
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Publication type | Journal article | |||||
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Upload Type | Publication | |||||
Title | ||||||
Niruriflavone, a new Antioxidant Flavone Sulfonic Acid from Phyllanthus niruri | ||||||
en | ||||||
Publication date | 2006 | |||||
Authors | ||||||
Ni Ni Than | ||||||
Fotso, S. | ||||||
Poeggeler, B. | ||||||
Hardeland, R. | ||||||
Laatsch, H. | ||||||
Description | ||||||
A new flavone sulfonic acid 1 named niruriflavone was isolated from the 70% ethanolic extract of the whole plant of Phyllanthus niruri (Euphorbiaceae), together with 6,10,14-trimethyl-2- pentadecanone, hypophyllanthin, gallic acid, brevifolin carboxylic acid, methyl brevifolin carboxylate, isoquercetin, quercetin-3-O-ß-D-glucopyranosyl(1→4)-α-rhamnopyranoside, corilagin, and isocorilagin, whose structures were determined by spectroscopic methods and comparison with published data. In an ABTS cation radical reduction assay, niruriflavone (1) exhibited potent radical scavenging properties. A biological test system based on bioluminescence of the dinoflagellate Lingulodinium polyedrum did not reveal any prooxidant properties of 1 at 50 μM. | ||||||
Keywords | ||||||
Phyllanthus niruri | ||||||
Journal articles | ||||||
A Journal of Chemical Sciences | ||||||
61 | ||||||
Conference papaers | ||||||
Books/reports/chapters | ||||||
Thesis/dissertations |