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  1. University of Yangon
  2. Department of Botany

Pharmacognostic Study on the Raw Materials Present in Some Medicinal Plants and Their Antimalarial Effect

http://hdl.handle.net/20.500.12678/0000002118
http://hdl.handle.net/20.500.12678/0000002118
49af7d7a-d13c-4cec-ab39-04a4f1cdf87e
1eeebad0-3d56-4f30-9ffc-2dd493be87a8
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Pharmacognostic Pharmacognostic study on the Raw Materials Present in some Medicinal Plants and their Antimalarial Effect.pdf (3775 Kb)
Publication type
Journal article
Upload type
Publication
Title
Title Pharmacognostic Study on the Raw Materials Present in Some Medicinal Plants and Their Antimalarial Effect
Language en
Publication date 2017
Authors
Khin Thazar
Sandar Aung
Moe Moe Lwin
Description
The selected plants Samanea saman (Jacq.) Merr. (Kalar-kokko) belongs to the family Mimosaceae; Daatyloctenium aegyptiwn (L.) Wild. (Myet-thone-kha) belongs to the family Poaceae; Brucea javanica (L.) Merr. (Yadan-zi) be longs to the family Simeroubaceae; Plwneria alba L. (Tayok-saga-aphyu) be longs to the family Apocynaceae and Ferula foetida Rega l. (Shein -go) belongs to the family Apiaceae. These plants are widely distributed in Myanmar. In morphological, sensory characters, macroscopical and diagnostic characters study of some medicinal plants of powdered simple and pitted vessels, fibres, fibre-tracheids, tracheids, lactiferous cells, oil cells and the fragments of epidermal cells. In physicochemical properties s of some medicinal plants, methanol extracts showed more soluble than other solvents. These some medicinal plants are locally well-known as especially antimalarial and also employed for the treatment of several cancer and various diseases. One of the potential sources of antimalarial drugs is traditional medicinal plants. This study is to determine the invitro antimalarial effect of methanolic extracts of combination of some medicinal plants on Plasmodium falciparum. Twenty blood samples from Plasmodium falciparum infected patients which fulfilled the selection criteria were investigated for in vitro drug sensitivity test (WHO, 1987, 200 1). Test doses of methanolic extracts of some medicinal plants were used ranging from (6.25-400 μg/ml). Methanolic extracts of combination of some medicinal plants showed significant antimalarial effect (EC50 values=19.44 μg/ml). Therefore this methanolic extracts of combination of some medicinal plants showed highly active antimalarial effect on
Plasmodium falciparum.
Keywords
antimalarial effect
Identifier https://uyr.uy.edu.mm/handle/123456789/655
Journal articles
1 & 2
Journal of the Asia Research Centre
6
Conference papaers
Books/reports/chapters
Thesis/dissertations
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