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  1. University of Yangon
  2. Department of Chemistry

Isolation of Active Organic Compounds from Phyllanthus Aibizzoides (Kurz Hook.f.) (Shit-Shar) and Phyllanthus Maderaspatensis L. (Taw-Zee-Phyu)

http://hdl.handle.net/20.500.12678/0000001927
http://hdl.handle.net/20.500.12678/0000001927
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490f8053-c111-4bf5-9b97-6110292a7028
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Isolation Isolation of Active Organic Compounds....pdf (378 Kb)
Publication type
Journal article
Upload type
Publication
Title
Title Isolation of Active Organic Compounds from Phyllanthus Aibizzoides (Kurz Hook.f.) (Shit-Shar) and Phyllanthus Maderaspatensis L. (Taw-Zee-Phyu)
Language en
Publication date 2016
Authors
Hla Ngwe
Myint Myint Khin
Khin Chaw Win
Myat Noe Hlaing
Theingi Phyo
Description
This research deals with the investigation of active organic compounds from the whole plant of Taw-zee-phyu, TZP (Phyllanthus maderaspatensis L.) and barks of Shit-shar, SS (Phyllanthus albizzioides (Kurz) Hook.f.). One compound, quercetin-3-O-β-D- glucopyranosyl (1-4) α-rhamnopyranoside from EtOAc extract of TZP and two compounds : lupeol and (E)-pentyl 3-3,4dihydroxyphenyl acrylate from pet-ether extract of SS bark were isolated by solvent extraction followed by column and thin layer chromatographic separation methods. The structures of isolated compounds were elucidated and identified by modern spectroscopic techniques such as UV, FT IR, 1H NMR, 13C NMR, 2DNMR such as 1H-1H COSY, NOESY, HSQC and HMBC, and ESI- MS.All of these isolated compounds showed the antioxidant activity in the order of : quercetin-3-O-β-D- glucopyranosyl (1-4) α- rhamnopyranoside (IC50= 2.50 μg/mL) > lupeol (IC50 = 4.97 μg/mL) > (E)-pentyl 3-3,4dihydroxyphenyl acrylate (IC50 = 7.78 μg/mL), determined by DPPH radical scavenging assay.
Keywords
Phyllanthus maderaspatensis
Identifier https://uyr.uy.edu.mm/handle/123456789/601
Journal articles
University of Yangon Research Journal
Conference papaers
Books/reports/chapters
Thesis/dissertations
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