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Item

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Merr.,\r Momordica charantia Linn., Spirulina and Syzygium grande (WI) Walp.. All of these medicinal\r plants have been reported to possess the antidiabetic potential. In the present work, watery and\r ethanolic extracts, and some isolated compounds such as lupeol, lupeol acetate, friedelin, betulinic\r acid, gallic acid, stigmasterol, taraxasterol, B-sitosterol-B-D-glucoside, stearic acid, B-sitosterol,\r vitamin C, charatin and A. xanthoides essential oil were used to investigate their inhibitory effect on a-\r glucosidase enzyme activity. All of the selected medicinal plant extracts (IC50 = 0.14 ~ 2.07 µg/ml) as\r well as the isolated compounds (IC50 = 0.47 ~ 1.91 µg/ml) were found to show the a-glucosidase\r inhibitory activity. These values were found to be comparable with Voglibose (IC50 = 0.32 µg/ml),\r which was used as a reference in this study. 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Investigation of the Bioactive Principles and α-Glucosidase Inhibitory Effect of some Myanmar Traditional Medicinal Plants

http://hdl.handle.net/20.500.12678/0000001890
6973fb08-cb98-4f85-b427-5d33e42b64a0
cffee391-4562-4f18-a5ae-89726e664964
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Investigation Investigation of the Bioactive Principles and α-Glucosidase.pdf (618 Kb)
Publication type
Conference paper
Upload type
Publication
Title
Title Investigation of the Bioactive Principles and α-Glucosidase Inhibitory Effect of some Myanmar Traditional Medicinal Plants
Language en
Publication date 2012
Authors
Hla Ngwe
Khin Chaw Win
May Mon Kyaw
Thaw Thaw Zin
Kyaw Thu
San San Maw
Description
This research is focused on the evaluation of a-glucosidase inhibitors from eight Myanmar
traditional medicinal plants such as Ammomum xanthoides Wall., Commelina communis Linn.,
Crataeva religiosa Forst., Eupatorium odoratum Linn., Gynura procumbens (Lour.) Merr.,
Momordica charantia Linn., Spirulina and Syzygium grande (WI) Walp.. All of these medicinal
plants have been reported to possess the antidiabetic potential. In the present work, watery and
ethanolic extracts, and some isolated compounds such as lupeol, lupeol acetate, friedelin, betulinic
acid, gallic acid, stigmasterol, taraxasterol, B-sitosterol-B-D-glucoside, stearic acid, B-sitosterol,
vitamin C, charatin and A. xanthoides essential oil were used to investigate their inhibitory effect on a-
glucosidase enzyme activity. All of the selected medicinal plant extracts (IC50 = 0.14 ~ 2.07 µg/ml) as
well as the isolated compounds (IC50 = 0.47 ~ 1.91 µg/ml) were found to show the a-glucosidase
inhibitory activity. These values were found to be comparable with Voglibose (IC50 = 0.32 µg/ml),
which was used as a reference in this study. Therefore these plants may be used as sources of natural
a-glucosidase inhibitors in control or management of the postprandial hyperglycemia, Type 2 diabetes.
Keywords
Myanmar traditional medicinal plants
Identifier http://uyr.uy.edu.mm/handle/123456789/95
Journal articles
Conference papaers
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Thesis/dissertations
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