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  1. University of Yangon
  2. Department of Chemistry

Investigation of Bioactive Constituents and the Antitumour principle from Butea monosperma

http://hdl.handle.net/20.500.12678/0000001825
http://hdl.handle.net/20.500.12678/0000001825
ede3640b-5caf-4e0c-ae2b-dd16faf8559d
086c4824-88e1-423f-9426-1184c1aae7d5
None
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Investigation Investigation of Bioactive Constituents and the Antitumour principle from Butea monosperma.pdf (239 Kb)
Publication type
Journal article
Upload type
Publication
Title
Title Investigation of Bioactive Constituents and the Antitumour principle from Butea monosperma
Language en
Publication date 2016
Authors
Ni Ni Than
Fiebig, Heinz-Herbert
Laatsch, Hartmut
Description
The ethanol extract of the flower of Butea monosperma
(Fabaceae) was found to contain butein (1), butin (2),
monospermoside (3), medicarpin-3-O-glucoside (4), ß-sitosterol
glucoside (5), sulphurein (6), isomonospermoside (7), isocoreopsin
(8), butrin (9), isobutrin (10) ergost-5-en-3ß-ol (11), stigmasterol
(12), ß-sitosterol (13), 6,10,14-trimethyl-2-pentadecanone (14),
methyl hexadecanoate(15), methyl octadecanoate (16), and
heptacosane (17), whose structures were determined by modern
spectroscopic techniques. In which, medicarpin-3-O-glucoside (4)
was isolated for the first time from this plant. The antitumour
activity of three pure compounds (1), (9) and (10) were tested by
using 6 human tumour cell lines. Compound (1) which showed
activity in the primary screening was further screened by 36
human tumour cell lines. Compound (1) showed mean IC70
value at 11.34 µg/mL and mean IC50 value at 7.39 µg/mL in the
ovarian tumour cell line.
Keywords
Butea monosperma
Identifier http://uyr.uy.edu.mm/handle/123456789/110
Journal articles
Conference papaers
Books/reports/chapters
Thesis/dissertations
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