{"created":"2021-01-28T07:24:47.811875+00:00","id":7860,"links":{},"metadata":{"_buckets":{"deposit":"ff7e29d2-60fe-4fc8-abe8-d167be61d54e"},"_deposit":{"created_by":100,"id":"7860","owner":"100","owners":[100],"owners_ext":{"displayname":"hlahlawin","email":"hhlawin2013@gmail.com","username":"hlahlawin"},"pid":{"revision_id":0,"type":"depid","value":"7860"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/00007860","sets":["1607984359018:1608053322572"]},"communities":["um2"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"HIV care in Yangon, Myanmar; successes, challengesand implications for policy","subitem_1551255648112":"en"}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"Background:  Approximately 0.8% of adults aged 18–49 in Myanmar are seropositive for Human Immunodeficiency Virus (HIV ). Identifying the demographic, epidemiological and clinical characteristics of people living with HIV (PLHIV ) is essential to inform optimal management strategies in this resource-limited country.Methods:  To create a “snapshot” of the PLHIV seeking anti-retroviral therapy (ART ) in Myanmar, data were collected from the registration cards of all patients who had been prescribed ART at two large referral hospitals in Yangon, prior to March 18, 2016.Results and discussion:  Anti-retroviral therapy had been prescribed to 2643 patients at the two hospitals. The patients’ median [interquartile range (IQR)] age was 37 (31–44) years; 1494 (57%) were male. At registration, inject-ing drug use was reported in 22 (0.8%), male-to-male sexual contact in eleven (0.4%) and female sex work in eleven (0.4%), suggesting that patients under-report these risk behaviours, that health care workers are uncomfortable enquiring about them or that the two hospitals are under-servicing these populations. All three explanations appear likely. Most patients were symptomatic at registration with 2027 (77%) presenting with WHO stage 3 or 4 disease. In the 2442 patients with a CD4+ T cell count recorded at registration, the median (IQR) count was 169 (59–328) cells/mm3. After a median (IQR) duration of 359 (185–540) days of ART, 151 (5.7%) patients had died, 111 (4.2%) patients had been lost to follow-up, while 2381 were alive on ART. Tuberculosis (TB) co-infection was common: 1083 (41%) were already on anti-TB treatment at registration, while a further 41 (1.7%) required anti-TB treatment during follow-up. Only 21 (0.8%) patients were prescribed isoniazid prophylaxis therapy (IPT ); one of these was lost to follow-up, but none of the remaining 20 patients died or required anti-TB treatment during a median (IQR) follow-up of 275 (235–293) days.Conclusions:  People living with HIV in Yangon, Myanmar are generally presenting late in their disease course, increasing their risk of death, disease and transmitting the virus. A centralised model of ART prescription struggles to deliver care to the key affected populations. TB co-infection is very common in Myanmar, but despite the proven efficacy of IPT, it is frequently not prescribed."}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value_mlt":[{"interim":"HIV"},{"interim":"Myanmar"},{"interim":"Anti-retroviral therapy"},{"interim":"Tuberculosis"},{"interim":"Isoniazid prophylaxis therapy"},{"interim":"Key affected populations"},{"interim":"Resource limited settings"}]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2021-01-28"}],"displaytype":"preview","filename":"HIV_care_in_Yangon_Myanmar_successes_challenges_an.pdf","filesize":[{"value":"755 KB"}],"format":"application/pdf","licensetype":"license_0","url":{"url":"https://meral.edu.mm/record/7860/files/HIV_care_in_Yangon_Myanmar_successes_challenges_an.pdf"},"version_id":"f5842048-0d32-4dcf-bfb1-fcfa07e010ca"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"14","subitem_journal_title":"AIDS Res Ther","subitem_pages":"1-7","subitem_volume":"10"}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Ne Myo Aung"},{"subitem_authors_fullname":"Hanson, Josh"},{"subitem_authors_fullname":"Tint Tint Kyi"},{"subitem_authors_fullname":"Zaw Win Htet"},{"subitem_authors_fullname":"Cooper, David A."},{"subitem_authors_fullname":"Boyd, Mark A."},{"subitem_authors_fullname":"Mar Mar Kyi"},{"subitem_authors_fullname":"Htin Aung Saw"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2021-01-28"},"item_title":"HIV care in Yangon, Myanmar; successes, challengesand implications for policy","item_type_id":"21","owner":"100","path":["1608053322572"],"publish_date":"2021-01-28","publish_status":"0","recid":"7860","relation_version_is_last":true,"title":["HIV care in Yangon, Myanmar; successes, challengesand implications for policy"],"weko_creator_id":"100","weko_shared_id":-1},"updated":"2021-12-13T00:26:22.297142+00:00"}