{"created":"2020-08-30T20:08:02.662166+00:00","id":3194,"links":{},"metadata":{"_buckets":{"deposit":"82f925d9-5af7-40e1-a50b-b1dc291ad79f"},"_deposit":{"id":"3194","owners":[],"pid":{"revision_id":0,"type":"recid","value":"3194"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/3194","sets":["1582963366982:1596631786153"]},"communities":["um1"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Insulin Receptor Substrate-1 Gene (G972R) Polymorphism and Insulin Resistance in Overweight and Obese Type 2 Diabetes Mellitus Patients","subitem_1551255648112":""}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"<p>The insulin receptor substrate-1 gene (IRS-1) gene has been considered a candidate for insulin resistance in type-2 diabetes and coronary artery disease. The most common IRS-1 variant, a glycine to arginine change at codon 972(G972R) is more prevalent among subjects who have features of insulin resistance syndrome associated with type 2 diabetes patients. The aim of the present study was to determine the insulin receptor substrate-1 gene (G972R) polymorphism and insulin resistance in overweight and obese type 2 diabetes mellitus patients. The genomic DNA of the subjects was amplified by polymerase chain reaction (PCR) and digested by restriction fragment length polymorphism (RFLP) with BstN1 used for codon 972.</p>"}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value_mlt":[{"interim":"IRS-1gene"},{"interim":"G972R"},{"interim":"Polymorphism"},{"interim":"T2DM"}]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-04-09"}],"displaytype":"preview","filename":"Insulin Receptor Substrate-1 Gene (G972R) Polymorphism and Insulin Resistance.pdf","filesize":[{"value":"132 Kb"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://meral.edu.mm/record/3194/files/Insulin Receptor Substrate-1 Gene (G972R) Polymorphism and Insulin Resistance.pdf"},"version_id":"df011498-281a-4ccf-8f98-5e8059dad578"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"1","subitem_journal_title":"Myanmar Health Sciences Research Journal","subitem_pages":"66-71","subitem_volume":"27"}]},"item_1583103147082":{"attribute_name":"Conference papers","attribute_value_mlt":[{"subitem_acronym":"","subitem_c_date":"","subitem_conference_title":"","subitem_part":"","subitem_place":"","subitem_session":"","subitem_website":""}]},"item_1583103211336":{"attribute_name":"Books/reports/chapters","attribute_value_mlt":[{"subitem_book_title":"","subitem_isbn":"","subitem_pages":"","subitem_place":"","subitem_publisher":""}]},"item_1583103233624":{"attribute_name":"Thesis/dissertations","attribute_value_mlt":[{"subitem_awarding_university":"","subitem_supervisor(s)":[{"subitem_supervisor":""}]}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Thae Nu Htwe"},{"subitem_authors_fullname":"Myat Mon Oo"},{"subitem_authors_fullname":"Saw Wut Hmon"},{"subitem_authors_fullname":"Moh Moh Htun"},{"subitem_authors_fullname":"Ohnmar Myint Thein"},{"subitem_authors_fullname":"Myat Thandar"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2015-12-24"},"item_1583159847033":{"attribute_name":"Identifier","attribute_value":"10.5281/zenodo.3745901"},"item_title":"Insulin Receptor Substrate-1 Gene (G972R) Polymorphism and Insulin Resistance in Overweight and Obese Type 2 Diabetes Mellitus Patients","item_type_id":"21","owner":"1","path":["1596631786153"],"publish_date":"2020-04-09","publish_status":"0","recid":"3194","relation_version_is_last":true,"title":["Insulin Receptor Substrate-1 Gene (G972R) Polymorphism and Insulin Resistance in Overweight and Obese Type 2 Diabetes Mellitus Patients"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2021-12-13T02:50:33.281783+00:00"}