{"created":"2020-08-30T20:01:37.195318+00:00","id":3139,"links":{},"metadata":{"_buckets":{"deposit":"1500b456-f71e-4998-85a0-dd90b6791239"},"_deposit":{"id":"3139","owners":[],"pid":{"revision_id":0,"type":"recid","value":"3139"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/3139","sets":["1582963366982:1596631591423"]},"communities":["um1"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"The presence of anti-basement membrane zone antibodies in the sera of patients with non-buUous lupus erythematosus","subitem_1551255648112":""}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"

We performed indirect immunotluorescence (IF) studies using 1 mol/1 sodium chloride split skin to determine whether or not a positive IF is specific to patients with hullous kipus erythematosus (LE). We examined the sera from 21 patients with systemic LE (SLE). three of which were ohtained from two SLE patients and one subacute cutaneous LE (SCLE) patient with bullous eruptions. As a comparison, we also studied the sera from patients with discoid LE (DLE. u = 71. SCLE (n = 1). systemic sclerosis fSSc. n = 20), hullous pemphigoid (n = 2) and normal individuals (n — 10). Sera from 16 SLE. four DLE and two SSc revealed a linear deposition of IgG isotype antibody at the epidermal side and/or the dermal side on indirect IF of split skin. The sera from three patients with bullous eruption and from 12 patients of SLE. SCLE. DLE without bullous eruption or SSc were further analysed by immunoblotting using live defined antigens, i.e. dermal extract, epidennal extract, three fusion proteins of 2 30 kDa bullous pemphigoid antigen (BPAG). 180 kDa BPAG. and human epidermolysis bullosa acquisita (EBA) antigen.

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