{"created":"2020-08-30T20:01:27.698975+00:00","id":3137,"links":{},"metadata":{"_buckets":{"deposit":"b0d96da3-c5fd-4804-9cad-b6f042e855cb"},"_deposit":{"id":"3137","owners":[],"pid":{"revision_id":0,"type":"recid","value":"3137"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/3137","sets":["1582963366982:1596631591423"]},"communities":["um1"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Catalase restores the altered mRNA expression of collagen and matrix metalloproteinases by dermal fibroblasts exposed to reactive oxygen species","subitem_1551255648112":""}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"<p>We investigated the effects of reactive oxygen species (ROS) on mRNA expression of&nbsp;proalphal (l) collagen, proalphal (lll) collagen, matrix metalloproteinases-1 (MMP-1), 72&nbsp;kDa type lV collagenase (MMP-2), and tissue inhibitor of metalloproteinase (TIMP-1) by&nbsp;normal human dermal fibroblasts in a novel three-dimensional culture. Fibroblasts&nbsp;exposed to ROS generated by the hypoxanthine-xanthine oxidase system revealed an&nbsp;increased mRNAexpression of MMP-1 and MMP-2 with a maximum at48 h and 72h after<br>\nexposure. A slight increase in the mRNA level of tissue inhibitor of metalloproteinase&nbsp;(TIMP-1) was observed.</p>"}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value":[]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-10-10"}],"displaytype":"preview","filename":"Catalase restores the altered mRNA expression of collagen.pdf","filesize":[{"value":"78 Kb"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://meral.edu.mm/record/3137/files/Catalase restores the altered mRNA expression of collagen.pdf"},"version_id":"0bc07045-f819-4c16-be0a-d68b4948fbc3"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"4","subitem_journal_title":"European Journal of Dermatology","subitem_pages":"37-379","subitem_volume":"16"}]},"item_1583103147082":{"attribute_name":"Conference papers","attribute_value_mlt":[{"subitem_acronym":"","subitem_c_date":"","subitem_conference_title":"","subitem_part":"","subitem_place":"","subitem_session":"","subitem_website":""}]},"item_1583103211336":{"attribute_name":"Books/reports/chapters","attribute_value_mlt":[{"subitem_book_title":"","subitem_isbn":"","subitem_pages":"","subitem_place":"","subitem_publisher":""}]},"item_1583103233624":{"attribute_name":"Thesis/dissertations","attribute_value_mlt":[{"subitem_awarding_university":"","subitem_supervisor(s)":[{"subitem_supervisor":""}]}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Zaw KK"},{"subitem_authors_fullname":"Yokoyama Y"},{"subitem_authors_fullname":"Abe M"},{"subitem_authors_fullname":"Ishikawa O"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2006-10-18"},"item_1583159847033":{"attribute_name":"Identifier","attribute_value":"10.5281/zenodo.3478842"},"item_title":"Catalase restores the altered mRNA expression of collagen and matrix metalloproteinases by dermal fibroblasts exposed to reactive oxygen species","item_type_id":"21","owner":"1","path":["1596631591423"],"publish_date":"2019-10-10","publish_status":"0","recid":"3137","relation_version_is_last":true,"title":["Catalase restores the altered mRNA expression of collagen and matrix metalloproteinases by dermal fibroblasts exposed to reactive oxygen species"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2021-12-13T05:48:34.732968+00:00"}