{"created":"2020-08-30T20:00:28.159837+00:00","id":3126,"links":{},"metadata":{"_buckets":{"deposit":"966f31a3-27d8-45a8-a23d-d66ee485e9cf"},"_deposit":{"id":"3126","owners":[],"pid":{"revision_id":0,"type":"recid","value":"3126"},"status":"published"},"_oai":{"id":"oai:meral.edu.mm:recid/3126","sets":["1582963366982:1597649530495"]},"communities":["um1"],"item_1583103067471":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_1551255647225":"Comparison of Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung and Normal Subjects","subitem_1551255648112":""}]},"item_1583103085720":{"attribute_name":"Description","attribute_value_mlt":[{"interim":"<p>Relation of inflammation and cancer can be proven in most of the studies.&nbsp;Epidermal growth factor receptor (EGFR) overexpression is one of the&nbsp;commonest causes of non-small cell carcinoma of lung cancer (NSCLC).&nbsp;Cyclooxygenase-2 (COX-2) enzyme and its products; prostaglandin,&nbsp;prostacyclin, thromboxane are involved in inflammation. The aim of the&nbsp;study was to compare the serum epidermal growth factor receptor and&nbsp;cyclooxygenase-2 levels between patients with non-small cell carcinoma of&nbsp;lung and healthy controls. This study included 53 patients diagnosed as&nbsp;NSCLC and 16 apparently healthy controls. In 53 patients, 3 patients were<br>\ndiagnosed as adenocarcinoma and 50 patients were diagnosed as squamous&nbsp;cell carcinoma (SCC) of lung. In both subjects, serum EGFR and COX-2&nbsp;levels were determined by ELISA. The mean serum EGFR and COX-2&nbsp;levels of NSCLC patients were significantly higher than those of healthy&nbsp;controls (170.10&plusmn;13.80 vs. 3.56&plusmn;0.48 ng/ml) and (13.21&plusmn;3.17 vs. 0.62&plusmn;&nbsp;0.15 ng/ml), respectively&nbsp;(p&lt;0.001 in both). Both the mean serum EGFR&nbsp;and COX-2 levels of SCC patients (172.10&plusmn;14.30 ng/ml and 13.60&plusmn;3.34<br>\nng/ml) were significantly higher than those of healthy controls (p&lt;0.001 in&nbsp;both).</p>"}]},"item_1583103108160":{"attribute_name":"Keywords","attribute_value_mlt":[{"interim":"Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung and Normal"}]},"item_1583103120197":{"attribute_name":"Files","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2019-08-21"}],"displaytype":"preview","filename":"Comparison of Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2.pdf","filesize":[{"value":"88 Kb"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://meral.edu.mm/record/3126/files/Comparison of Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2.pdf"},"version_id":"6dff5551-bfc5-4b4c-8975-a52289b921a9"}]},"item_1583103131163":{"attribute_name":"Journal articles","attribute_value_mlt":[{"subitem_issue":"1","subitem_journal_title":"Myanmar Health Sciences Research Journal","subitem_pages":"11-15","subitem_volume":"28"}]},"item_1583103147082":{"attribute_name":"Conference papers","attribute_value_mlt":[{"subitem_acronym":"","subitem_c_date":"","subitem_conference_title":"","subitem_part":"","subitem_place":"","subitem_session":"","subitem_website":""}]},"item_1583103211336":{"attribute_name":"Books/reports/chapters","attribute_value_mlt":[{"subitem_book_title":"","subitem_isbn":"","subitem_pages":"","subitem_place":"","subitem_publisher":""}]},"item_1583103233624":{"attribute_name":"Thesis/dissertations","attribute_value_mlt":[{"subitem_awarding_university":"","subitem_supervisor(s)":[{"subitem_supervisor":""}]}]},"item_1583105942107":{"attribute_name":"Authors","attribute_value_mlt":[{"subitem_authors":[{"subitem_authors_fullname":"Thuzar Kyin Aung"},{"subitem_authors_fullname":"Htar Kyi Sunn"},{"subitem_authors_fullname":"Theingi Myint"}]}]},"item_1583108359239":{"attribute_name":"Upload type","attribute_value_mlt":[{"interim":"Publication"}]},"item_1583108428133":{"attribute_name":"Publication type","attribute_value_mlt":[{"interim":"Journal article"}]},"item_1583159729339":{"attribute_name":"Publication date","attribute_value":"2016-04-01"},"item_1583159847033":{"attribute_name":"Identifier","attribute_value":"10.5281/zenodo.3373274"},"item_title":"Comparison of Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung and Normal Subjects","item_type_id":"21","owner":"1","path":["1597649530495"],"publish_date":"2019-08-21","publish_status":"0","recid":"3126","relation_version_is_last":true,"title":["Comparison of Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung and Normal Subjects"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-03-24T23:15:13.016296+00:00"}