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  1. University of Yangon
  2. Department of Botany

Screening of Some Medicinal Plants for Their Antimicrobial Activity Against Escherichia coli

https://meral.edu.mm/records/10707
https://meral.edu.mm/records/10707
e49fbe1e-fa1a-480a-8717-9b29e7e813c8
360abe55-0c8e-47e2-9176-0bae737b60f8
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Publication type
Journal article
Upload type
Publication
Title
Title Screening of Some Medicinal Plants for Their Antimicrobial Activity Against Escherichia coli
Language en
Publication date 2024-10-31
Authors
Ni Ni Htun
Htay Htay Myint
thinzar
Description
Abstract
Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy
individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal
diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe
public health problem and a major cause of morbidity and mortality in infants and young children,
especially in developing countries. Myanmar has a rich pool of medicinal plants with traditional
knowledge. This study, therefore, aimed to investigate the inhibitory activity of traditional
Myanmar medicinal plants against E. coli. Firstly, the medicinal plants which treated diarrhea in
Myanmar Traditional Medicine were investigated. Depending upon the information obtained
from the investigation, the plants were collected from University of Yangon Campus, Nat-yekwin Village and Hla-pa-da Village (Hmawbi Township) and Hlawga National Park and then
identified based on morphological characters of plants. Some plant materials are purchased from
traditional drug shops and identified by organoleptic and microscopic evaluation methods of
crude drugs. In this research, EtOH extracts of total 45 plant samples were used to screen the
inhibitory activity against Escherichia coli with agar well diffusion method. The results of
experiments showed that among the 45 plant samples, the leaf powder of Acacia concinna (Kin
mon chin) was proofed to be most effective on the growth inhibition of Escherichia coli. The
second and third most effective samples were bark powder of Terminalia chebula and fruit
powder of Terminalia citrina. Leaves of Acalypha indica, rhizome of Zingiber montanum, seed
of Piper nigrum, rhizome of Curcuma longa, leaves of Morinda angustifolia, leaves of Eclipta
prostrata and leaves of Annona squamosa show weak activities on E. coli. Rhizome of Canna
indica has no activity.
Keywords
E.coli, Plant extracts, Medicinal plants, Antibacterial activity
Journal articles
2024
Journal of Asia Research Centre, University of Yangon
P.62-76
Vol.10, No. 1 & 2, 2024
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