2026-06-27T21:32:34Z https://meral.edu.mm/oai

oai:meral.edu.mm:recid/3029 2021-12-13T07:00:53Z 1582963366982 1582963366982:1597649184558 user-um1

Association between HLA-B* 15:02 and carbamazepine induced severe cutaneous adverse drug reactions in Myanmar Amy Hui-Ping Khor Seinn Mya Mya Aye Kheng-Seang Lim Yan Lynn Aung Yin Minn Aye Ohnmar Win Min Thit Chong-Tin Tan Ching-Ching Ng Genetic predisposition to carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) had been reported in several Southeast Asian populations, but not in Myanmar. Previous studies had so far reported more than 70% of CBZ-induced SJS/TEN cases positive for HLA-B*15:02 allele.1-4 Myanmar, as the second largest country in Southeast Asia with a population of 54.5 million, has high HLA-B*15:02 carrier frequency in its general population (27.3- 49.1%).5,6. 2017-12-15 http://hdl.handle.net/20.500.12678/0000003029 https://meral.edu.mm/records/3029