2026-06-23T23:04:43Z https://meral.edu.mm/oai

oai:meral.edu.mm:recid/2215 2021-12-13T06:40:08Z 1582963390870:1582967769683 user-uy

Production of Biologically Active Compounds from Endophytic Strains Isolated from Different Plant Species Ko Tin Aye Aye Oo Thwe Thwe Oo Yee Yee Thu In screening of the bioactive compounds from microbial source, seven endophytic fungal strains were isolated from different plan species in this research. These fungal strains YT1 to YT7 indicated antimicrobial activity by paper disc diffusion assay. For extraction and isolation of the bioactive compounds, the methanol extracts of the most active strains were eluted on silica gel, flash silica gel, Sephadex LH20 gel columns with various solvent systems. The isolated compounds were identified and characterized by spectroscopic techniques. The two compounds: Butyrolactone I and Aspulvinone O from strain YTI and Terreusinone from strain YT3 were isolated from six liter fermentation of each strain. All isolated compounds indicated antimicrobial activity on eight test organisms in 5 μg of 1.0mg/mL invitro. 2016 http://hdl.handle.net/20.500.12678/0000002215 https://meral.edu.mm/records/2215