2026-07-27T23:15:12Z https://meral.edu.mm/oai

oai:meral.edu.mm:recid/00007879 2021-12-13T04:31:09Z 1607984359018:1608053322572 user-um2

The clinical characteristics of adults with rheumatic heart disease in Yangon, Myanmar: Anobservation a lstudy Nan Phyu Sin Toe Myint Ne Myo Aung Myint Soe Win Thu Ya Htut Ralph, Anna P. Cooper, David A. Myo Lwin Nyein Mar Mar Kyi Hanson, Josh BackgroundRheumaticheartdisease(RHD)is a majorcauseof prematuredeathin lowandmiddle-incomecountries.Thegreatestbarrierto RHDcontrolis neglectof thediseasein nationalhealthpoliciesanda lackof prevalencedatathatmightinformcontrolefforts.Myanmarismakingremarkableprogressagainstmanyinfectiousdiseases,buttherearealmostnodatato definetheclinicalburdenof RHDin thecountry.Thisprospective auditwasperformedinanadultmedicalwardof a tertiary-referralhospitalin Yangon,to gainaninsightintotheprevalenceof RHDin Myanmar.PrincipalfindingsAllpatientsadmittedto thewardbetweenMay1, 2016andApril30,2017wereeligibleforenrolment.RHDwasconfirmedin 96patientswhowereadmittedon134occasions,repre-senting1.1%of the12,172adultmedicaladmissionsduringthestudyperiod.Thiscom-paredwith410(3.4%)admissionswithHIVand14(0.1%)withmalaria.PatientswithRHDhada medianageof 44years(interquartilerange:35–59);70(73%)werefemale.Onlyonepatienthadeverhadsurgerydespite79(82%)meetingcriteriaforintervention;54(56%)patientswerenotreceivinganyregularclinicianreview.Priorto hospitalisationonly18(19%)patientswerereceivingregularpenicillin.Only8 (19%)of the42women<50yearswereusingcontraception.Of49patientswhohadbeenhospitalisedpreviously,22(45%)werereceivingnoregulartherapy.Duringthestudythree(3.1%)patientsdied,and28(29%)werelostto follow-up.Ofthe65(68%)aliveandretainedin care,21(32%)werestillexperiencingmoderate-severeRHD-relatedsymptomsat thestudy’send.ConclusionsThereis a significantandunmetclinicalburdenof RHDin Myanmar.A nationalRHDprogram-mewouldimprovepatientcare,reducingmorbidityandmortalityfromthispreventabledisease. 2018-02-21 http://hdl.handle.net/20.500.12678/0000007879 https://meral.edu.mm/records/7879